Key Facts About Joint Infections
The growth in total joint replacement (TJR) surgeries and infection of total joint replacement implants is being driven in part by an increasing elderly population of people living longer, with increasing incidence of obesity and diabetes among many factors driving increasing amounts of both osteoarthritis and TJR infection. Implant sepsis can present serious health risks to patients. Revision surgery to replace an infected implant costs 4-6 times more than a primary joint replacement procedure, and infection of joint implants can have a devastating effect on patient quality of life.
4.5 million Americans currently live with total knee replacement in at least one knee, which is nearly 5 percent of the population age 50 and older. TJR rates have risen risen steadily during the past two decades in the US – reaching 620,192 knees and 284,708 hip implant procedures in 2009 in the U.S. alone.
Currently, patients undergoing revision surgery to correct a septic implant experience a 50% recurrence of infection after surgery. 80% of implant infections are staphylococcal infections – the type of infection targeted by TPH 101.